Behold the Sinister Six!

Norman Osborn can't be blocked. Whenever Norman Osborn deals combat damage to a player, he connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.) 1UBR: Transform Norman Osborn. Activate only as a sorcery.

Flying You don't lose unspent red mana as steps and phases end. Whenever you cast an instant or sorcery spell, add R. When Electro leaves the battlefield, you may pay X. When you do, he deals X damage to target player.

When Mysterio enters, create a 3/3 blue Illusion Villain creature token for each nontoken Villain you control. Exile those tokens when Mysterio leaves the battlefield.

Mind Swap — You may have Superior Spider-Man enter as a copy of any creature card in a graveyard, except his name is Superior Spider-Man and he's a 4/4 Spider Human Hero in addition to his other types. When you do, exile that card.

Web-slinging W (You may cast this spell for W if you also return a tapped creature you control to its owner's hand.) As Arachne enters, look at an opponent's hand, then choose a card type other than creature. Spells of the chosen type cost 1 more to cast.

Riot (This creature enters with your choice of a +1/+1 counter or haste.) Other Spiders you control have riot. Spells and abilities can't be countered. Damage can't be prevented.

Web-slinging RG (You may cast this spell for RG if you also return a tapped creature you control to its owner's hand.) Trample Sensational Save — If Scarlet Spider was cast using web-slinging, he enters with X +1/+1 counters on him, where X is the mana value of the returned creature.

Deathtouch, lifelink Whenever Gwenom attacks, until end of turn, you may look at the top card of your library any time and you may play cards from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.